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DeCS
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Descriptor English:
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beta 2-Microglobulin
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Descriptor Spanish:
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Microglobulina-2 beta
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Descriptor Portuguese:
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Microglobulina-2 beta
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Synonyms English:
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2-Microglobulin, beta
beta 2 Microglobulin
Thymotaxin
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Tree Number:
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D12.776.124.790.223.100
D12.776.377.715.182.100
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Definition English:
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An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants. |
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Indexing Annotation English:
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/biosyn /physiol /blood permitted
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History Note English:
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91(75); was BETA 2 MICROGLOBULIN 1984-90; was see under BETA GLOBULINS 1975-83
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Allowable Qualifiers English:
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Record Number:
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29233
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Unique Identifier:
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D001613
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Occurrence in VHL:
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Similar:
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DeCS CID-10 LILACS
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